What is Sanger sequencing?

DNA sequencing was invented in the UK by double-Nobel-prizewinning scientist Fred Sanger. The Sanger method of DNA sequencing relied on the natural ability of DNA to copy itself, using a builder enzyme. The builder enzyme made many partial copies of a piece of DNA. Copying was halted at either an A, C, G or T base. Scientists carried out DNA sequencing by repeating this process in four separate test tubes – one with copies stopped at all the As, one at the Cs, one at the Gs and one at the Ts.

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Principal Funder:

Wellcome trust

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GlaxoSmithKline life technologies